Amyotrophic lateral sclerosis (ALS) is a late-onset fatal neurodegenerative disease reflecting degeneration of upper and lower motoneurons (MNs).The cause of ALS and the mechanisms of neuronal death are still largely obscure, thus impairing the establishment of efficacious therapies.Glutamate (Glu)-mediated excitotoxicity plays a major role in MN d
Final plea for conservation of Gaultheria akaensis Panda and Sanjappa (Ericaceae), an extremely threatened, endemic medicinal plant from Aka Hill in Arunachal Pradesh of eastern Himalaya, India
Since its discovery in Flour 2002 from Aka Hill in Arunachal Pradesh, the population of Gaultheria akaensis Panda and Sanjappa, a Critically Endangered, endemic medicinal plant is on the verge of extinction and currently represented by two individuals only.No trace of this species found in other Himalayan parts of India as well in Nepal, Bhutan, Ch
Pasteurization and the Potential Anti-Obesity Function of Fermented Beverages: A Significant Increase in Nitrogen-Containing Aromatic Heterocyclic Compound Content
Obesity is a chronic disease that profoundly impacts human health, and the role of plant-based formulas (PBFs) in combating obesity has garnered significant interest.Studies have revealed that fermentation significantly enhances the taste, aroma, quality, and health benefits Vitamins of PBF water extract, with pasteurization being the preferred ste
Reversible Regulation of Cell Cycle-Related Genes by Epigallocatechin Gallate for Hibernation of Neonatal Human Tarsal Fibroblasts
We investigated the hibernation effect of epigallocatechin-3- O -gallate (EGCG) on neonatal human tarsal fibroblasts (nHTFs) by analyzing the expression of cell cycle-related genes.EGCG application to culture media moderately inhibited the growth of nHTFs, and the removal of EGCG from culture media led to complete recovery of cell growth.EGCG resul